Prof. Dr. Jana Seifert

  • Director Department of Functional Microbiology of Livestock (460c)

  • Equal Opportunities Officer (Faculty Agricultural Sciences)

Emil-Wolff-Str. 8
Room 116
+49 711 459 24284
seifert.jana@uni-hohenheim.de

 

CV

Jana Seifert studied Geoecology at the Technical University Bergakademie Freiberg, Germany. During her studies she got fascinated about microbiology and decided to move on this subject. She did her PhD in biology about the degradation of chloroaromatic hydrocarbons by gram-positive bacteria. As a Post-Doc she focused on geomicrobiology and analyzing microbial communities with molecular-genetic techniques. As a group leader at the Helmholtz Center for Environmental Research – UFZ in Leipzig, Germany she started to focus on the functionality of microbial communities setting up metaproteomics and protein-SIP. 2013 to 2018 she was a junior professor, since 2019 she is a full professor at the University of Hohenheim, Germany, where she works on the microbiome-animal interaction and the use of feeding resources by the gut microbiome.

Projects

Host-Microbiome Interaction: Implications for cellular and global energy metabolism of dairy cows (WiMiQ)

WiMiQ

2024- 2026

In collaboration with FLI Braunschweig (Dr J. Frahm, Prof. S. Dänicke), Uni Bonn (Prof. H. Sauerwein)

 
Publications

from previous project MitoCow

Tröscher-Mußotter J, Saenz JS, Grindler S, Meyer J, Kononov SU, Mezger B, Borda-Molina D, Frahm J, Dänicke S, Camarinha-Silva A, Huber K, Seifert J (2021) Microbiome clusters disclose physiologic variances in dairy cows challenged by calving and lipopolysaccharides.

mSystems 6(5):e00856; doi.org/10.1128/mSystems.00856-21

Tröscher-Mußotter J, Deusch S, Borda-Molina D, Frahm J, Dänicke S, Camarinha-Silva A, Huber K, Seifert J (2022) Cow’s microbiome from antepartum to postpartum: A long-term study covering two physiological challenges.

Frontiers in Microbiology 13. doi: 10.3389/fmicb.2022.1000750

Microbial and host myo-inositol usage in the gastrointestinal tract of laying hens

Project in the DFG Research Unit ‘Appearance and physiological relevance of inositol phosphates and myo-inositol in the domesticated fowl’ FOR 2601

Project time: 2022-2025

People
Groups

PiFerm - Using peas as pig feed: Impact of fermentable carbohydrates, bacterial fermentation and enzymes on nutrient digestibility and microbiota

2023-2026
Funding: Bundesanstalt für Landwirtschaft und Ernährung

Groups

This is a collaborative project with Prof. Amélia Camarinha-Silva und Prof. Markus Rodehutscord.

 

 

Impact of microbial-formed indole-3-propionic acid on the host’s metabolism and health

Partnership program The Hebrew University of Jerusalem – University of Hohenheim

2024-2025

Dr. Kfir Sharabi (Institute of Biochemistry, Food Science and Nutrition, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem)

 

 

Interplay between fermentative and respiratory energy conservation in Prevotella sp.

Start: 2017
DFG (SE 2059/3-1)

People
Publications

 

Deusch S, Bok E, Schleicher L, Seifert J, Steuber J (2019) Occurrence and function of the Na+-translocating NADH:Quinone oxidoreductase in Prevotella spp. Microorganisms 7(5), 117, doi: 10.3390/microorganisms7050117

Schleicher L, Fritz G, Seifert J, Steuber J (2020) Anoxic cell rupture of Prevotella bryantii by high-pressure homogenization protects the Na+-translocating NADH:quinone oxidoreductase from oxidative damage. Archive of Microbiology 202, 1263–1266, doi: 10.1007/s00203-019-01805-x

Trautmann A, Schleicher L, Deusch S, Gätgens J, Steuber J, Seifert J (2020) Short-chain fatty acids modulate metabolic pathways and membrane lipids in Prevotella bryantii B14. Proteomes. 8, 28; doi:10.3390/proteomes8040028

Schleicher L, Trautmann A, Stegmann D, Fritz G, Gätgens J, Bott M, Hein S, Simon J, Seifert J, Steuber J (2021) A sodium-translocating module linking succinate production to formation of a membrane potential in Prevotella bryantii. Applied and Environmental Microbiology. doi.10.1128/AEM.01211-21.

Trautmann A, Schleicher L, Pfirrmann J, Boldt C, Steuber J, Seifert J (2021) Na+-coupled respiration and reshaping of extracellular polysaccharide layer counteract monensin-induced cation permeability in Prevotella bryantii B14. International Journal of Molecular Sciences 22: 10202; doi.10.3390/ijms221910202.

Trautmann A, Schleicher L, Koch A, Günther J, Steuber J, Seifert J. (2022) A shift towards succinate-producing Prevotella in the ruminal microbiome challenged with monensin. Proteomics. e2200121. doi: 10.1002/pmic.202200121

 

Hau JL, Schleicher L, Herdan S, Simon J, Seifert J, Fritz G, Steuber J (2023) Functionality of the Na+-translocating NADH:quinone oxidoreductase and quinol:fumarate reductase from Prevotella bryantii inferred from homology modeling. Archives in Microbiology. 206(1):32. doi: 10.1007/s00203-023-03769-5.

Protein efficiency in pigs - Protipig

Start: 01.08.2019
Wilhelm Schaumann Stiftung

People
Collaborators

This is a collaborative project together with Prof. Amélia Camarinha-Silva, Prof. Markus Rodehutscord and Prof. Jörn Bennewitz.

Publications

Kurz A, Seifert J (2021) Factors Influencing Proteolysis and Protein Utilization in the Intestine of Pigs: A Review.

Animals 11(12):3551; doi.org/10.3390/ani11123551

Sarpong N, Seifert J, Bennewitz J, Rodehutscord M, Camarinha-Silva A (2024) Microbial signatures and enterotype clusters in fattening pigs: implications for nitrogen utilization efficiency.

Frontiers in Microbiology.15. doi: 10.3389/fmicb.2024.1354537

Schmid M, Weishaar R, Seifert J, Camarinha-Silva A, Rodehutscord M, Bennewitz J (2024) Genomic analyses of nitrogen utilization efficiency, its indicator trait blood urea nitrogen and the relationship to classical growth performance and feed efficiency traits in a Landrace x Piétrain crossbred population.

Journal of Animal Breeding and Genetics. doi: 10.1111/jbg.12864

 

 

 

Publications

publication list